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Persistent HIV infection works a lot like cancer, study shows. Preferential activation of capecitabine in tumor following oral administration in colorectal cancer patients. However, unlike parenterally administered 5-FU, oral capecitabine concentrates predominantly in tumor tissue as opposed to adjacent healthy tissue and plasma [ 15 ]. Xeloda capecitabine Tablets Prescribing Information. Continuous 5-fluorouracil in the treatment of breast cancer. Discuss safety and dosing considerations Describe current adjuvant treatment with capecitabine. In fact, a recent survey sponsored by Pfizer Oncology shows just how misunderstood it is. Roche Laboratories Inc. Responses Submit a response No responses published. Based on promising findings in patients previously treated for metastatic disease, single-agent oral capecitabine is being investigated for treating earlier treatment settings of breast cancer. Breast Cancer Res Treat . Efficacy and safety of single agent capecitabine in pretreated metastatic breast cancer patients from the French compassionate use program. How could that happen. Patients, experts discuss ins and outs of sharing a diagnosis. Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer.

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Description: Capecitabine monotherapy or combined with taxanes. J Clin Oncol . 22 14S. Current Issue February , 24 2. However, there were three treatment-related deaths among patients treated with single-agent capecitabine corticosteroid-induced diabetes mellitus, bronchopneumonia, and unknown cause. Compared with other therapies for second-line or later metastatic breast cancer, single-agent oral capecitabine appears to be cost-effective. Although there are relatively few new trials of single-agent capecitabine for the treatment of breast cancer, capecitabine-based combination therapies are currently under investigation. Medline Google Scholar. But with MBC, the treatment philosophy is different. Pollastro went on Herceptin, a type of immunotherapy for women with HER2-positive metastatic breast cancer, and did six months of chemotherapy. Oral capecitabine is an active and well tolerated primary palliative treatment in patients with metastatic breast cancer who progress after high dose chemotherapy and autologous stem cell support.
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